Molecular Profiles™

Pharmaceutical Development Services

The Queen’s Awards for Enterprise: Innovation 2011

Handling some samples
Team studying some samples

Key techniques

When you need additional resource and expertise, we deliver through the application of the most appropriate, cutting-edge technologies. Our diverse toolkit includes:

Spectroscopy and chemical mapping

  • Confocal Raman microscopy
  • Infrared and ATR infrared
  • FT Raman
  • Micro-FTIR and micro-ATR
  • Time-of-flight secondary ion mass spectrometry
  • X-ray photoelectron spectroscopy (ESCA)
  • UV-VIS
  • NMR

Physical Properties

  • X-ray diffraction (variable temperature and humidity)
  • DSC / GVS / TGA
  • Light scattering particle size / photocorrelation spectroscopy / disc centrufigation / sieving
  • BET / mercury porosimetry
  • Isothermal microcalorimetry
  • Karl Fischer
  • Surface plasmon resonance / quartz crystal microbalance

Microscopy

  • Atomic force microscopy (AFM) / environmental AFM
  • Scanning thermal microscopy and nanothermal microscopy
  • Micro x-ray computer tomography
  • SEM / EDAX / environmental SEM / TEM
  • Confocal laser scanning microscopy
  • Optical (hot stage) microscopy

Chromatography and compendial testing

  • HPLC / ion chromatography / gas chromatography / mass spectroscopy
  • Dissolution / intrinsic dissolution / disintegration / hardness

Protein characterisation

  • HPLC / LC-MS / UV / FTIR / SEC-HPLC
  • SDS-PAGE / native PAGE / isoelectric focussing / western blotting
  • Peptide mapping